Product-focused R&D

Formulation Development and Deformulation

Laboratory investigation of pharmaceutical formulations to understand composition, performance and analytical characteristics and to support the development or improvement of pharmaceutical products.

Understand and improve pharmaceutical formulations

Formulation development involves balancing the properties of the active pharmaceutical ingredient, excipients, dosage form and intended use. Phanso supports product-focused investigations to help answer formulation and analytical questions with laboratory data.

Deformulation, also described as formulation reverse engineering, involves the analytical investigation and characterization of an existing product. Depending on the product and question, this can help inform comparative assessments, development work or investigation of unexpected product behaviour.

Areas of support

  • Formulation screening and development support
  • Investigation of excipient compatibility and formulation behaviour
  • Comparative characterization of existing products
  • Analytical investigation of formulation composition
  • Support for formulation-related stability questions
  • Analytical method development to characterize product components

When formulation investigation can help

Independent analytical work can help clarify product behaviour and guide the next development step.

Product comparison

Investigate similarities and differences between formulations or product samples using suitable analytical approaches.

Excipient and API questions

Explore analytical questions related to active ingredients, excipients, solubility or compatibility.

Unexpected product behaviour

Support investigations into appearance changes, assay shifts, degradation or other formulation-related observations.

Development decisions

Generate focused data to help evaluate formulation options and determine useful follow-up work.

Have a formulation question to investigate?

Describe the product, what is known and what you need to understand.

Contact Phanso